Uninhabited except by a few small fishing hamlets and one tourist resort, Mitsio is a collection of small islands 40 nautical miles north east of Nosy Be affording excellent diving and snorkelling on vibrant fringing coral reefs. Each island has a unique character; eg La Grande Mitsio is known for its huge basalt columns (the Organ Pipes).
A climb up the highest hill on Nosy Ankarea (219m), passing many interesting succulents en route, reveals spectacular views over the entire archipelago. Sunrise and sunset are the best times to visit Les Quatre Frères (the Four Brothers), islands of silver basalt containing huge caves with impressive overhangs and nesting seabirds such as northern gannets, white-tailed tropicbirds, and frigatebirds.